Publications

Ryan’s Google Scholar and NIH My Bibliography

Underline indicates members of the Williams Lab!

Published:

38. Yamaguchi S, Sedaka R, Kapadia C, Huang J, Hsu JS, Berryhill TF, Wilson L, Barnes S, Lovelady C, Oduk Y, Williams RM, Jaimes EA, Heller DA, and Saigusa T. (2024) Rapamycin-encapsulated nanoparticle delivery in polycystic kidney disease mice. Scientific Reports 15140. Link Download

37. Ryan A, Rahman S, and Williams RM. (2024) An optical aptamer-based nanosensor detects macrophage activation by bacterial toxins. ACS Sensors. Link Download

Ryan A, Rahman S, and Williams RM. (2024) An optical aptamer-based nanosensor detects macrophage activation by bacterial toxins. bioRxiv Preprint. Link Download

36.       Gaikwad P, Rahman N, Ghosh P, Ng D, and Williams RM. (2024) Rapid differentiation of estrogen receptor status in patient biopsy breast cancer aspirates with an optical nanosensor. bioRxiv Pre-Print (2024). Link Download

35.       Vasylaki A^, Ghosh P^, Jaimes EA, & Williams RM. (2024) Targeting the kidneys at the nanoscale: Nanotechnology in nephrology. Kidney360 of the American Society of Nephrology 5:618-630. Link Download

34. Cohen Z, Alpert DJ, Weisel AC, Ryan A, Roach A, Rahman S, Gaikwad PV, Nicoll SB, and Williams RM. (2024) Noninvasive injectable optical nanosensor-hydrogel hybrids detect doxorubicin in living mice. Advanced Optical Materials Link Download

Cohen Z, Alpert DJ, Weisel AC, Roach A, Rahman S, Gaikwad PV, Nicoll SB, and Williams RM. (2023) Noninvasive injectable optical nanosensor-hydrogel hybrids detect doxorubicin in living mice. bioRxiv Preprint. Link Download

33. Gaikwad P, Rahman N, Parikh R, Crespo J, Cohen Z, and Williams RM. (2024) Optical nanosensor passivation enables highly sensitive detection of the inflammatory cytokine IL-6. ACS Applied Materials & Interfaces 16:27102-27113. Link Download

Gaikwad P, Rahman N, Parikh R, Crespo J, Cohen Z, and Williams RM. (2023) Optical nanosensor passivation enables highly sensitive detection of the inflammatory cytokine IL-6. bioRxiv Preprint. Link Download

32. Kubala JM, Laursen KB, Schreiner R, Williams RM, van der Mijn JC, Crowley MJ, Mongan NP, Nanus DM, Heller DA, and Gudas LJ. (2023) NDUFA4L2 reduces mitochondrial respiration resulting in defective lysosomal trafficking in clear cell renal cell carcinoma. Cancer Biology and Therapy 24: 2170669 Link Download

31. Cohen Z, Parveen S, and Williams RM. (2022) Optimization of ssDNA-SWCNT ultracentrifugation via efficacy measurements. ECS Journal of Solid State Science and Technology 11:101009. Link Download

30. Skelton R*, Roach A*, Prudhomme LE, Cen Feng HYC, Gaikwad P, and Williams RM. (2022) Formulation of lipid-free polymeric mesoscale nanoparticles encapsulating mRNA. Pharmaceutical Research. (co-first authors) Link Download

29. Verias LC, Bernstein E, Cao D-Y, Okwan Duodu D, Khan Z, Gibb DR, Roach A, Skelton A, Williams RM, Bernstein KE, and Giani JF. (2022) Tubular IL-1β induces salt sensitivity in diabetes by activating renal macrophages. Circulation Research 131:59-73. Link Download [Editorial Commentary in Pitzer et al. 2022 Circulation Research 131:74-76]  

28. Benson LN, Liu Y, Wang X, Xiong Y, Rhee SW, Guo Y, Deck KS, Mora CJ, Li L, Huang L, Andrews JT, Qin Z, Hoover RS, Ko B, Williams RM, Heller DA, Jaimes EA, and Mu S. (2022) The IFNγ-PDL1 pathway enhances CD8T-DCT interaction to promote hypertension. Circulation Research 130: 1550-1564. Link Download

27.       Williams RM, Shah J, Mercer E, Tian HS, Thompson V, Cheung JM, Dorso M, Kubala J, Gudas LJ, de Stanchina E Jaimes EA, and Heller DA. (2022) Kidney-Targeted Redox Scavenger Therapy Prevents Cisplatin-Induced Acute Kidney Injury. Frontiers in Pharmacology, Renal Pharmacology 12: 790913. Link Download

Williams RM, Shah J, Mercer E, Tian HS, Dorso M, Jaimes EA, and Heller DA. (2020) Renal peritubular capillary transcytosis of mesoscale nanoparticles mediates therapy of acute kidney injury. bioRxiv Preprint Link Download

26. Guo X, Xu L, Velazquez H, Chen T, Williams RM, Heller DA, Burtness B, Safirstein R, and Desir G. (2021) Kidney-Targeted Renalase Agonist Prevents Cisplatin-Induced Chronic Kidney Disease by Inhibiting Regulated Necrosis and Inflammation. Journal of the American Society of Nephrology.33:342-356. [Commentary in Curry and McCormick (2022) JASN 33:255-256] Link Download

25.       Williams RM, Kapadia C, Jaimes EA, and Heller DA. (2021) Chapter 31 Nanotargeting to the Kidney. In “Regenerative Nephrology” 2nd Edition. Editor Michael S. Goligorsky. Published by Elsevier Link

24.       Williams RM*, Chen S*, Langenbacher RE, Galassi TV, Harvey JD, Jena PV, Budhathoki-Uprety J, Luo M, and Heller DA. (2021) Nanochemical Biology: harnessing nanotechnology to expand the toolbox of chemical biology. Nature Chemical Biology 17: 129-137. (* co-first authors) Link Download

23.       Han SJ, Williams RM, Kim M, Heller DA, D’Agatti V, Schmit-Supprian M, and Lee HT. (2020) Renal proximal tubular NEMO plays a critical role in ischemic acute kidney injury. JCI Insight. 5(19): e139246. Link Download

22.       Williams RM, Harvey JD, Budhathoki-Upreti J, and Heller DA. (2020) Glutathione-S-transferase Fusion Protein Nanosensor. Nano Letters 20: 7287-7295. Link Download

21.       Han SJ, Williams RM, D’Agati VD, Jaimes EA, Heller DA, and Lee HT. (2020) Selective nanoparticle-mediated targeting of renal tubular TLR9 attenuates ischemic acute kidney injury. Kidney International 98: 76-87. [Highlighted in Commentary: Endre and Erlich (2020) Kidney International 98:48-50] Link Download

20.       Harvey JD*, Williams RM*, Tully KM, Baker HA, Shamay Y, and Heller DA. (2019) An in vivo nanosensor measures compartmental doxorubicin exposure. Nano Letters 19: 4343-4354. (* co-first authors) Link Download

19.       Williams RM, Lee, C, and Heller DA. (2018) A fluorescent carbon nanotube sensor detects the metastatic prostate cancer biomarker uPA. ACS Sensors 3: 1838-1845. Link Download

18.       Williams RM, Lee C, Galassi TV, Harvey JD, Leicher R, Sirenko M, Dorso M, Shah J, Olvera N, Dao F, Levine DA, and Heller DA. (2018) Non-invasive ovarian cancer biomarker detection via an optical nanosensor implant. Science Advances 4: eaaq1090; Link Download

17.       Williams RM, Shah J, Tian HS, Chen X, Geissmann F, Jaimes EA, and Heller DA. (2018) Selective nanoparticle targeting of the renal tubules. Hypertension 71: 87-94; [Highlighted in Perspective: Yap et al. (2018) Hypertension 71: 61-63] Link Download

16.       Harvey JD, Jena PV, Baker HA, Zerze GH, Williams RM, Galassi TV, Roxbury D, Mittal J, and Heller DA. (2017) A carbon nanotube reporter of miRNA hybridization events in vivo. Nature Biomedical Engineering 1: 0041. [Highlighted in News and Views: Lazaro and Kostarelos (2017) Nature Biomedical Engineering 1: 0063] Link Download

15.       Budhathoki-Uprety J, Harvey JD, Isaac E, Williams RM, Galassi TV, Langenbacher RE, and Heller DA. (2017) Polymer cloaking modulates the carbon nanotube protein corona and delivery in cancer cells. Journal of Materials Chemistry B 5: 6637-6644. Link Download

14.       Williams RM, Jaimes EA, and Heller DA. (2016) Nanomedicines for kidney diseases. Kidney International 90:740-745. Link Download

13.       Williams RM, Shah J, Ng BD, Minton DR, Gudas LJ, Park CY, and Heller DA. (2015) Mesoscale nanoparticles selectively target the renal proximal tubule epithelium. Nano Letters 15(4): 2358-2364 Link Download

12.       Hong KL, Imlay K, Battistella L, Williams RM, Hickey K, Bostick C, Gannett PM, and Sooter LJ. (2015) Selection of single-stranded DNA molecular recognition elements against Exotoxin A using a novel Decoy-SELEX method and sensitive detection of Exotoxin A in human serum. BioMed Research International 2015: 41764 Link Download

11.       Roxbury D, Jena PV, Williams RM, Enyedi B, Niethammer P, Marcet S, Verhaegen M, Blais-Ouellette S, and Heller DA. (2015) Hyperspectral Microscopy of Near-Infrared Fluorescence Enables 17-Chirality Carbon Nanotube Imaging. Scientific Reports 5: 14167. Link Download

10.       Williams RM and Sooter LJ. (2015) In vitro selection of cancer cell-specific molecular recognition elements from amino acid libraries. The Journal of Immunology Research 2015: 18686 Link Download

9.         Hong KL, Maher E, Williams RM, and Sooter LJ. (2015) In vitro selection of single-stranded DNA molecular recognition elements against Toxin B and sensitive detection in human fecal matter. The Journal of Nucleic Acids 2015:808495 Link Download

8.         Hong KL, Battistella L, Salva AD, Williams RM, and Sooter LJ. (2015) In vitro selection of single-stranded DNA molecular recognition elements against S. aureus alpha toxin and sensitive detection in human serum. International Journal of Molecular Sciences 16(2): 2794-2809 Link Download

7.         Williams RM, Kulick AR, Yedlapalli S, Battistella L, Hajiran CJ, Sooter LJ. (2014) Isolation of single-stranded DNA molecular recognition elements against bromacil. The Journal of Nucleic Acids 2014: 102968 Link Download

6.         Williams RM, Hajiran CJ, Nayeem S, and Sooter LJ. (2014) Identification of an antibody fragment molecular recognition element specific for androgen-dependent prostate cancer cells. BMC Biotechnology 14:81 [Highlighted as Editor’s Pick] Link Download

5.         Williams RM, Maher E, and Sooter LJ. In vitro selection of a ssDNA molecular recognition element for the pesticide malathion. (2014) Combinatorial Chemistry & High Throughput Screening 17(8): 694-702 Link Download

4.         Williams RM, Taylor H, Thomas J, Hines B, and Sooter LJ. (2014)  The effect of DNA- and sodium cholate-dispersed single wall carbon nanotubes on the green algae Chlamydomonas reinhardtii. The Journal of Nanoscience 2014:419382 Link Download

3.         Williams RM, Crihfield CL, Gattu S, Holland LA, and Sooter LJ. (2014) In vitro selection of a single-stranded DNA molecular recognition element against atrazine. International Journal of Molecular Sciences 15(8): 14332-14347 Link Download

2.         Williams RM, Nayeem S, Hines B, and Sooter LJ. (2014) The effect of DNA-dispersed single-wall carbon nanotubes on the polymerase chain reaction. PLoS ONE 9(4): e94117 Link Download

1.         Williams RM and Naz RK. (2010) Novel biomarkers and therapeutic targets for prostate cancer. Frontiers in Bioscience S2:677-684. Link Download